Classic KS tends to occur in which population?

Classic KS tends to occur in which population?

• A. HIV-positive individuals with systemic disease
• B. Children with congenital lesions
• C. Immunocompromised patients with facial nodules
• D. Older men without HIV

Answer: (D)

Classic Kaposi sarcoma is the form that appears in older men of certain Mediterranean or Eastern European descents who are HIV-negative. It tends to be indolent and localized, often starting on the legs. This distinct epidemiology sets it apart from the AIDS-associated form (seen in HIV-positive individuals, often younger with broader disease), the iatrogenic form (in immunosuppressed patients such as transplant recipients), and the African/endemic form (which can affect younger people in Africa, including children). So the population most characteristic of classic KS is older men without HIV.

Classic Kaposi sarcoma is the form that appears in older men of certain Mediterranean or Eastern European descents who are HIV-negative. It tends to be indolent and localized, often starting on the legs. This distinct epidemiology sets it apart from the AIDS-associated form (seen in HIV-positive individuals, often younger with broader disease), the iatrogenic form (in immunosuppressed patients such as transplant recipients), and the African/endemic form (which can affect younger people in Africa, including children). So the population most characteristic of classic KS is older men without HIV.