Classic Kaposi sarcoma classically presents in which demographic and pattern?

Classic Kaposi sarcoma classically presents in which demographic and pattern?

• A. HIV-associated KS with systemic symptoms
• B. Older men with red-purple plaques on distal extremities
• C. Pediatric patients with mucocutaneous nodules
• D. Immunocompromised women with facial lesions

Answer: (B)

Classic Kaposi sarcoma is most characteristically seen in elderly men of Mediterranean or Eastern European descent. The hallmark pattern is slowly progressive, violaceous to red-purple patches or plaques on the distal extremities, most often the legs and ankles. This indolent, skin-limited presentation on the distal legs distinguishes the classic form from other KS variants that involve younger patients, trunk or mucosal sites, or have a more aggressive course. So, older men with red-purple plaques on the distal extremities fit this pattern best.

Classic Kaposi sarcoma is most characteristically seen in elderly men of Mediterranean or Eastern European descent. The hallmark pattern is slowly progressive, violaceous to red-purple patches or plaques on the distal extremities, most often the legs and ankles. This indolent, skin-limited presentation on the distal legs distinguishes the classic form from other KS variants that involve younger patients, trunk or mucosal sites, or have a more aggressive course. So, older men with red-purple plaques on the distal extremities fit this pattern best.